Protein glycosylation pathways in filamentous fungi
نویسندگان
چکیده
منابع مشابه
Protein glycosylation pathways in filamentous fungi.
Glycosylation of proteins is important for protein stability, secretion, and localization. In this study, we have investigated the glycan synthesis pathways of 12 filamentous fungi including those of medical/agricultural/industrial importance for which genomes have been recently sequenced. We have adopted a systems biology approach to combine the results from comparative genomics techniques wit...
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Due to its natural properties, Trichoderma reesei is commonly used in industry-scale production of secretory proteins. Since almost all secreted proteins are O-glycosylated, modulation of the activity of enzymes of the O-glycosylation pathway are likely to affect protein production and secretion or change the glycosylation pattern of the secreted proteins, altering their stability and biologica...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2008
ISSN: 1460-2423,0959-6658
DOI: 10.1093/glycob/cwn044